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Crack propagation with different radius local random damage based on peridynamic theory

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5,   Pages 1238-1248 doi: 10.1007/s11709-021-0695-y

Abstract: Drawing from the advantages of Classical Mechanics, the peridynamic theory can clarify the crack propagationmechanism by an integral solution without initially setting the factitious crack and crack path.This study implements the peridynamic theory by subjecting bilateral notch cracked specimens to the conditionsMoreover, to study the effects of local stochastic damage with different radii on the crack propagationand Y-direction displacement, a comparison and contact methodology was adopted, in which the crack

Keywords： peridynamics     stochastic damage     bilateral notch crack    

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Peridynamics versus XFEM: a comparative study for quasi-static crack problems

Jinhai ZHAO, Hesheng TANG, Songtao XUE

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 4,   Pages 548-557 doi: 10.1007/s11709-017-0434-6

Abstract: However, capturing of complex mixed-mode crack patterns has been proven to be difficult with PD.extended finite element method (XFEM) is one of the most popular methods for fracture which allows crackThe first example is crack propagation in a double notched specimen under uniaxial tension with differentcrack spacings in loading direction.

Keywords： XFEM     peridynamic     bilateral crack     parallel double cracks     nonlocal theory    

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Mechanical responses of pristine and defective hexagonal boron-nitride nanosheets: A molecular dynamics investigation

Mohammad SALAVATI, Arvin MOJAHEDIN, Ali Hossein Nezhad SHIRAZI

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 3,   Pages 623-631 doi: 10.1007/s11709-020-0616-5

Abstract: In this work we conducted classical molecular dynamics (MD) simulation to investigate the mechanical characteristics and failure mechanism of hexagonal boron-nitride (h-BN) nanosheets. Pristine and defective structure of h-BN nanosheets were considered under the uniaxial tensile loadings at various temperatures. The defective structure contains three types of the most common initial defects in engineering materials that are known as cracks, notches (with various length/size), and point vacancy defects (with a wide range of concentration). MD simulation results demonstrate a high load-bearing capacity of extremely defective (amorphized) h-BN nanosheets. Our results also reveal that the tensile strength decline by increasing the defect content and temperature as well. Our MD results provide a comprehensive and useful vision concerning the mechanical properties of h-BN nanosheets with/without defects, which is very critical for the designing of nanodevices exploiting the exceptional physics of h-BN.

Keywords： hexagonal boron-nitride     mechanical properties     crack     notch     point defects     molecular dynamics    

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Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 442-458 doi: 10.1007/s11684-021-0877-y

Abstract: More than 60% of T-ALL patients carry NOTCH1 gene mutations, leading to abnormal expression ofHDAC inhibitor, exerts an antitumor effect on T-ALL cell lines and primary cells including an anti-NOTCH1In particular, chidamide inhibits the NOTCH1-MYC signaling axis by down-regulating the level of the intracellularform of NOTCH1 (NICD1) as well as MYC, partly through their ubiquitination and degradation by the proteasomethe effectiveness and safety of chidamide in the treatment of T-ALL patients, including those with NOTCH1

Keywords： T-cell acute lymphoblastic leukemia     HDAC inhibitor     chidamide     NOTCH1     MYC     ubiquitination    

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Parametric equations for notch stress concentration factors of rib–deck welds under bending loading

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 3,   Pages 595-608 doi: 10.1007/s11709-021-0720-1

Abstract: The effective notch stress approach for evaluating the fatigue strength of rib–deck welds requires notchFirst, we developed a model for investigating the effective notch stress in rib–deck welds.parametric analysis to investigate the effects of multiple geometric parameters of a rib–deck weld on the notchstepwise regression analysis was performed to obtain the optimal regression functions for predicting the notchThe notch stress concentration factors estimated from the developed formulas show agree well with the

Keywords： notch stress concentration factor     rib–deck weld     parametric analysis     regression analysis     parametric    

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Demand response based congestion management in a mix of pool and bilateral electricity market model

Ashwani KUMAR, Charan SEKHAR

Frontiers in Energy 2012, Volume 6, Issue 2,   Pages 164-178 doi: 10.1007/s11708-012-0187-9

Abstract: In this paper, demand response-based CM has been proposed for a mix of pool and bilateral electricityThe bilateral demand has been obtained with minimum deviations in their preferred schedule.

Keywords： bid function     congestion management (CM)     demand response     pool+bilateral electricity market     static var    

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Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract: regenerative capacity because of the active participation of various signaling pathways, including Wnt and NotchThe Wnt and Notch pathways are highly sophisticated and conserved signaling pathways that control multipleIn this regard, Wnt and Notch signaling has gained increased research attention in hair cell regenerationThis review presents the current understanding of the Wnt and Notch signaling pathways in the auditory

Keywords： inner ear     cochlea     hair cell     regeneration     Wnt     Notch     signaling pathways    

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Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 705-712 doi: 10.1007/s11684-019-0703-y

Abstract: Wnt and Notch signaling play crucial roles in the determination of the prosensory domain and in the differentiationHere, we investigated the interactions between Notch and Wnt signaling on the basis of the bidirectionalregulation of Notch1 specifically in Wnt-responsive Lgr5 progenitors during different cochlear developmentWe found that the downregulation of Notch1 in Lgr5 cells from embryonic day (E) 14.5 to E18.5 can driveOur findings improved the understanding of the interactions between Notch and Wnt signaling in cochlear

Keywords： inner ear     cochlear     Wnt     Notch     Lgr5     auditory system    

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Numerical investigation on the dryout point of annular flow in the upward narrow annuli with bilateral

SU Guanghui, QIU Suizheng, DUAN Feng, XIAO Zejun, HUANG Yanping

Frontiers in Energy 2007, Volume 1, Issue 3,   Pages 264-272 doi: 10.1007/s11708-007-0037-3

Abstract: has been developed to predict the dryout point of upward annular flow in vertical narrow annuli with bilateral
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Dynamic crack propagation in plates weakened by inclined cracks: an investigation based on peridynamics

A. SHAFIEI

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 4,   Pages 527-535 doi: 10.1007/s11709-018-0450-1

Abstract: In this paper by using peridynamics, the crack path for inclined crack under dynamic loading were investigatedThe peridynamics solution for this problem represents the main features of dynamic crack propagationsuch as crack bifurcation.In addition, the influence of geometry on inclined crack growth is studied.

Keywords： peridynamics     inclined crack     dynamic fracture     crack branching    

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Prevention of laryngeal webs through endoscopic keel placement for bilateral vocal cord lesions

Jian Chen, Yilai Shu, Matthew R. Naunheim, Min Chen, Lei Cheng, Haitao Wu

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 301-306 doi: 10.1007/s11684-017-0549-0

Abstract: In this study, we retrospectively reviewed 54 patients who underwent microsurgery for bilateral lesionskeel placement could be an effective method for preventing anterior glottic webs after surgery for bilateral

Keywords： glottic stenosis     glottic web     laryngeal keel     silastic sheets     anterior commissure    

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Correlation between tension softening relation and crack extension resistance in concrete

Xiufang ZHANG , Shilang XU ,

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 3,   Pages 323-329 doi: 10.1007/s11709-009-0041-2

Abstract: Changes of the material fracture energy consumption with crack propagation can be described by a crackextension resistance curve, one of the fundamental fracture criteria in crack mechanics.observation of the fracture behavior in concrete was used to develop a new fracture criterion, the crackextension resistance curve, to analyze crack propagation during the entire concrete fracture processfracture process zone ahead of the stress-free crack tip.

Keywords： concrete     fracture process zone     crack extension GR resistance     tension softening curve    

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Regeneration of hair cells in the mammalian vestibular system

Wenyan Li,Dan You,Yan Chen,Renjie Chai,Huawei Li

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 143-151 doi: 10.1007/s11684-016-0451-1

Abstract: regeneration and subsequent functional recovery of the vestibular system, including manipulating the Wnt, Notch

Keywords： utricle     hair cell     regeneration     Atoh1     Notch     Wnt    

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Fracture resistance on aggregate bridging crack in concrete

ZHANG Xiufang, XU Shilang

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 1,   Pages 63-70 doi: 10.1007/s11709-007-0006-2

Abstract: Utilizing the obtained load against crack opening displacement curve, the value of G at any crack extensionas well as the change of G with the crack extension is examined.It is found that G will firstly increase with the development of crack and then stay constant once theinitial crack tip opening displacement reaches the characteristic crack opening displacement w0.The results reveal that the values of G of different specimens at any crack propagation are strongly
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Stability and dynamics of rotor system with 45° slant crack on shaft

Yanli LIN, Xiaohui SI, Fulei CHU

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 2,   Pages 203-213 doi: 10.1007/s11465-011-0131-4

Abstract:

Crack on a shaft is one of the common damages in a rotor system.slant crack on the rotor system.is larger than that with a transverse crack when the two types of crack have the same depth and thetorsional excitation are analyzed by considering opening and closing of the crack.on a shaft and can be used for the detection of the slant crack on a shaft.

Keywords： rotor dynamics     slant crack     stability     torsional excitation     open and close    

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Title Author Date Type Operation

Crack propagation with different radius local random damage based on peridynamic theory

Journal Article

Peridynamics versus XFEM: a comparative study for quasi-static crack problems

Jinhai ZHAO, Hesheng TANG, Songtao XUE

Journal Article

Mechanical responses of pristine and defective hexagonal boron-nitride nanosheets: A molecular dynamics investigation

Mohammad SALAVATI, Arvin MOJAHEDIN, Ali Hossein Nezhad SHIRAZI

Journal Article

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Journal Article

Parametric equations for notch stress concentration factors of rib–deck welds under bending loading

Journal Article

Demand response based congestion management in a mix of pool and bilateral electricity market model

Ashwani KUMAR, Charan SEKHAR

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Journal Article

Numerical investigation on the dryout point of annular flow in the upward narrow annuli with bilateral

SU Guanghui, QIU Suizheng, DUAN Feng, XIAO Zejun, HUANG Yanping

Journal Article

Dynamic crack propagation in plates weakened by inclined cracks: an investigation based on peridynamics

A. SHAFIEI

Journal Article

Prevention of laryngeal webs through endoscopic keel placement for bilateral vocal cord lesions

Jian Chen, Yilai Shu, Matthew R. Naunheim, Min Chen, Lei Cheng, Haitao Wu

Journal Article

Correlation between tension softening relation and crack extension resistance in concrete

Xiufang ZHANG , Shilang XU ,

Journal Article

Regeneration of hair cells in the mammalian vestibular system

Wenyan Li,Dan You,Yan Chen,Renjie Chai,Huawei Li

Journal Article

Fracture resistance on aggregate bridging crack in concrete

ZHANG Xiufang, XU Shilang

Journal Article

Stability and dynamics of rotor system with 45° slant crack on shaft

Yanli LIN, Xiaohui SI, Fulei CHU

Journal Article